Pharmaceutical intermediates

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Chloroquine Phosphate

CAS: 50-63-5 Cat No: JKN00586 Purity: 98%

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Product Description

CAS 50-63-5 Cat No JKN00586
Name Chloroquine Phosphate
Synonyms Chloroquine phosphate
Smiles CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O
Chemical Name 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;phosphoric acid
Formula C18H32ClN3O8P2 MWt 515.9
Purity 98% Storage Store at 4--8℃
Description Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine may also interfere with the biosynthesis of nucleic acids.

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