+86 137 2013 4139
+86 137 2013 4139
| CAS: | 252917-06-9 | Cat No: | JKN00206 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 252917-06-9 | Cat No | JKN00206 | |
| Name | CHIR-99021 | |||
| Synonyms | CHIR911 | |||
| Smiles | N#CC1=CN=C(NCCNC2=NC=C(C3=NC(C)=CN3)C(C4=CC=C(Cl)C=C4Cl)=N2)C=C1 | |||
| Chemical Name | 6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile | |||
| Formula | C22H18Cl2N8 | MWt | 465.34 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Laduviglusib, also known as CHIR-99021 and CT99021, is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. CHIR-99021 inhibits GSK-3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 for proliferation is about 10μM. | |||
Product Documents
Menu
Contact Us
Tel: +86 137 2013 4139
E-mail: orders@jknbiochem.com
Add.:Room 2120, Office Building 2, No.1 Baisha Fifth Road, Hongshan District, Wuhan City, Hubei Province, China
Get In Touch
Get In Touch
