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| CAS: | 193273-69-7 | Cat No: | JKN00282 | Purity: | 98% |
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Product Description
| CAS | 193273-69-7 | Cat No | JKN00282 | |
| Name | Capromorelin tartrate | |||
| Synonyms | CP424 | |||
| Smiles | CC(C)(N)C(N[C@@H](C(N(C[C@]12CC3=CC=CC=C3)CCC1=NN(C)C2=O)=O)COCC4=CC=CC=C4)=O.O[C@H]([C@H](C(O)=O)O)C(O)=O | |||
| Chemical Name | 2-amino-N-((R)-1-((R)-3a-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-3-(benzyloxy)-1-oxopropan-2-yl)-2-methylpropanamide (2R,3R)-2,3-dihydroxysuccinate | |||
| Formula | C32H41N5O10 | MWt | 655.705 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Capromorelin, also known as CP-424,391, is a growth hormone secretagogue and ghrelin mimetic ( hGHS-R1a K(i)=7 nM, rat pituicyte EC(50)=3 nM). Initial studies have shown the drug to directly raise insulin growth factor 1 (IGF-1) and growth hormone levels. Capromorelin showed enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%]. This short-duration GHS was orally active in canine models and was selected as a development candidate for the treatment of musculoskeletal frailty in elderly adults. | |||
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