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| CAS: | 80994-59-8 | Cat No: | JKN00216 | Purity: | 98% |
Note: All products of the company are for scientific research only, and do not provide products and services for any individual
Product Description
| CAS | 80994-59-8 | Cat No | JKN00216 | |
| Name | Borofalan B10 | |||
| Synonyms | BorofalanB10 | |||
| Smiles | [10B](C1=CC=C(C=C1)C[C@@H](C(=O)O)N)(O)O | |||
| Chemical Name | (S)-2-amino-3-(4-(borono-10B)phenyl)propanoic acid | |||
| Formula | C9H1210BNO4 | MWt | 208.210 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Boronophenylalanine B-10 (also known as BPA) is a radiation sensitizer that contains 10B, a stable isotope of boron. Borofalan (10B) is a boronated phenylalanine and boron (boron-10) carrier that may be used in boron neutron capture therapy (BNCT), with potential antineoplastic activity. Upon administration, borofalan (10B) is absorbed mostly by tumor cells. When exposed to neutron irradiation, borofalan (10B) absorbs neutrons and self-destructs releasing short-range alpha radiation and 'recoil' lithium in tumor cells, resulting in alpha radiation-induced tumor cell death. This highly selective, localized radiotargeting of tumor cells spares adjacent normal tissues. | |||
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