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Home - Products-JKN Signaling Pathways-Boc-Val-Cit-PABA

Boc-Val-Cit-PABA

CAS:

870487-09-5

Cat No:

JKN03300

Purity:

98%

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Product Description

CAS	870487-09-5	Cat No	JKN03300
Name	Boc-Val-Cit-PABA
Synonyms	Boc-Val-Cit-PABA
Smiles	CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)NC(=O)OC(C)(C)C
Chemical Name	tert-butyl N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(hydroxymethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
Formula	C23H37N5O6	MWt	479.6
Purity	98%	Storage	Store at 4--8℃
Description	Boc-Val-Cit-PAB is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group。

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E-mail: orders@jknbiochem.com

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