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CAS: | 606143-89-9 | Cat No: | JKN00311 | Purity: | 98% |
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Product Description
CAS | 606143-89-9 | Cat No | JKN00311 | |
Name | Binimetinib | |||
Synonyms | MEK162 | |||
Smiles | O=C(C1=C(NC2=CC=C(Br)C=C2F)C(F)=C3N=CN(C)C3=C1)NOCCO | |||
Chemical Name | 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide. | |||
Formula | C17H15BrF2N4O3 | MWt | 441.227 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | Binimetinib, also known as MEK162 (ARRY-162), is an oral, highly selective MEK inhibitor. In preclinical studies, MEK162 showed significant antitumor activities in cell lines and animal models. MEK162 is the first targeted therapy to show activity in patients with NRAS -mutated melanoma and might offer a new option for a cancer with few effective treatments. |
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