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| CAS: | 2664214-60-0 | Cat No: | JKN02931 | Purity: | 98% |
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Product Description
| CAS | 2664214-60-0 | Cat No | JKN02931 | |
| Name | BI-4020 | |||
| Synonyms | BI-4020 | |||
| Smiles | C[C@@H]1CCCOC2=C(C=NN2C)C3=NC(=CC(=C3)C(=O)NC4=NC5=C(N4C1)C=C(C=C5)CN6CCN(CC6)C)C | |||
| Chemical Name | (11R)-5,11,26-trimethyl-16-[(4-methylpiperazin-1-yl)methyl]-7-oxa-4,5,13,20,22,27-hexazapentacyclo[22.3.1.02,6.013,21.014,19]octacosa-1(27),2(6),3,14(19),15,17,20,24(28),25-nonaen-23-one | |||
| Formula | C30H38N8O2 | MWt | 542.7 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | BI-4020 is a macrocycle with formula C30H38N8O2. It is a potent inhibitor of triple mutant EGFR(del19 T790M C797S) variant and shows efficacy for regressing tumor xenografts in vivo. It has a role as an epidermal growth factor receptor antagonist and an antineoplastic agent. It is a N-methylpiperazine, a macrocycle, a pyridinecarboxamide, a member of pyrazoles, an ether and a member of indoles. | |||
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