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CAS: | 2893809-51-1 | Cat No: | JKN02917 | Purity: | 98% |
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Product Description
CAS | 2893809-51-1 | Cat No | JKN02917 | |
Name | BBO-8520 | |||
Synonyms | BBO-8520 | |||
Smiles | C[C@@H]1CN([C@H](CN1C(=O)C=C)C)C2=NC(=NC3=C(C(=C(C=C32)C(F)(F)F)C4=C5C(=C(SC5=C(C=C4)F)N)C#N)F)OC[C@@]67CCCN6C[C@@H](C7)F | |||
Chemical Name | 2-amino-4-[4-[(2S,5R)-2,5-dimethyl-4-prop-2-enoylpiperazin-1-yl]-8-fluoro-2-[[(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]-6-(trifluoromethyl)quinazolin-7-yl]-7-fluoro-1-benzothiophene-3-carbonitrile | |||
Formula | C35H33F6N7O2S | MWt | 729.7 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | BBO-8520 is a direct small molecule covalent inhibitor targeting KRASG12C, with high oral availability, and has both KRASG12C (OFF) inhibitor properties and the effect of blocking KRAS G12C (ON) signaling. |
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