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| CAS: | 319460-85-0 | Cat No: | JKN00534 | Purity: | 98% |
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Product Description
| CAS | 319460-85-0 | Cat No | JKN00534 | |
| Name | Axitinib | |||
| Synonyms | Axitinib | |||
| Smiles | CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4 | |||
| Chemical Name | N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide | |||
| Formula | C22H18N4OS | MWt | 386.5 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Axitinib is an indazole substituted at position 3 by a 2-(pyridin-2-yl)vinyl group and at position 6 by a 2-(N-methylaminocarboxy)phenylsulfanyl group. Used for the treatment of advanced renal cell carcinoma after failure of a first line systemic treatment. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a vascular endothelial growth factor receptor antagonist. It is a member of indazoles, a member of pyridines, an aryl sulfide and a member of benzamides. | |||
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