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CAS: | 1374248-81-3 | Cat No: | JKN00317 | Purity: | 98% |
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Product Description
CAS | 1374248-81-3 | Cat No | JKN00317 | |
Name | Atogepant | |||
Synonyms | MK8031 | |||
Smiles | O=C(C1=CN=C2C(C[C@@]3(C4=CC=CN=C4NC3=O)C2)=C1)N[C@@H]5C(N(CC(F)(F)F)[C@H](C)[C@H](C6=C(F)C=CC(F)=C6F)C5)=O | |||
Chemical Name | (3'S)-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl]-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide | |||
Formula | C29H23F6N5O3 | MWt | 603.525 | |
Purity | 98% | Storage | Store at 4--8℃ | |
Description | Atogepant, also known as MK-8031 and AGN 241689, is a calcitonin gene-related peptide receptor antagonist. Atogepant belongs to the “gepants” class of drugs that work by blocking cell receptors for CGRP, a protein released at the trigeminal nerve during migraine. Gepants have been shown to reduce future attacks by about 50 percent. Atogepant was approved in Sept 2021 to prevent episodic migraines. |
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