Pharmaceutical intermediates

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Atogepant

CAS: 1374248-81-3 Cat No: JKN00317 Purity: 98%

Note: All products of the company are for scientific research only, and do not provide products and services for any individual

Product Description

CAS 1374248-81-3 Cat No JKN00317
Name Atogepant
Synonyms MK8031
Smiles O=C(C1=CN=C2C(C[C@@]3(C4=CC=CN=C4NC3=O)C2)=C1)N[C@@H]5C(N(CC(F)(F)F)[C@H](C)[C@H](C6=C(F)C=CC(F)=C6F)C5)=O
Chemical Name (3'S)-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl]-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
Formula C29H23F6N5O3 MWt 603.525
Purity 98% Storage Store at 4--8℃
Description Atogepant, also known as MK-8031 and AGN 241689, is a calcitonin gene-related peptide receptor antagonist. Atogepant belongs to the “gepants” class of drugs that work by blocking cell receptors for CGRP, a protein released at the trigeminal nerve during migraine. Gepants have been shown to reduce future attacks by about 50 percent. Atogepant was approved in Sept 2021 to prevent episodic migraines.

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