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| CAS: | 955365-80-7 | Cat No: | JKN00392 | Purity: | 98% |
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Product Description
| CAS | 955365-80-7 | Cat No | JKN00392 | |
| Name | Adavosertib | |||
| Synonyms | MK-1775 | |||
| Smiles | CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O | |||
| Chemical Name | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one | |||
| Formula | C27H32N8O2 | MWt | 500.6 | |
| Purity | 98% | Storage | Store at 4--8℃ | |
| Description | Adavosertib is a member of the class of pyrazolopyrimidines that is 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one substituted by 6-(2-hydroxypropan-2-yl)pyridin-2-yl, prop-1-en-3-yl, [4-(4-methylpiperazin-1-yl)phenyl]amino groups at positions 1, 2, and 6, respectively. It is a potent and selective oral inhibitor of WEE1 kinase. It has a role as an antineoplastic agent and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a pyrazolopyrimidine, a member of pyridines, a tertiary alcohol, a secondary amino compound, a N-arylpiperazine and a N-methylpiperazine. | |||
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